Propylene Glycol SDS MSDS of Suppliers Exporters, CAS 57-55-6

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Propylene Glycol USP JP BP Ph Eur IP EP FCC Food Grade Manufacturers

Propylene Glycol
USP JP BP Ph Eur IP EP FCC Food Grade CAS Number 57-55-6, Commercial & Pure
Propylene Glycol

Propylene Glycol SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet

1. PRODUCT DESCRIPTION

Product Name & Other Names: Propylene Glycol or 1,2-Propanediol
CAS Number: 57-55-6
EINECS EC Number: 200-338-0
Molecular Weight: 76.09
Molecular Formula: CH3CH(OH)CH2OH
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Supplier: As per letterhead.

2. HAZARD IDENTIFICATION

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Hazard Class and Category Code(s), Regulation (EC) No 1272/2008 (CLP)

Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.

Labeling as per GHS & Regulation EC 1272/2008 (CLP) & GHS

GHS Label Elements
None

Signal Words: None

Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.

3. COMPOSITION/INFORMATION ON INGREDIENTS

Product Name & Other Names: Propylene Glycol or 1,2-Propanediol
CAS Number: 57-55-6
EINECS EC Number: 200-338-0

4. FIRST AID MEASURES

Always get medical attention after the first aid is over.

Emergency and First Aid Procedures:
Eyes - Flush with water for at least 15 minutes, raising and lowering eyelids occasionally. Get medical attention if irritation persists.
Skin - Thoroughly wash exposed area for at least 15 minutes. Remove contaminated clothing. Launder contaminated clothing before reuse. Get medical attention if irritation persists.
Ingestion - If it is swallowed, if conscious, give plenty of water. Immediately call a physician. Never give anything by mouth to an unconscious person.
Inhalation - Remove to fresh air. Give oxygen if breathing is difficult; give artificial respiration if breathing has stopped. Get medical attention.

5. FIREFIGHTING PROCEDURES

Extinguisher Media: Use media suitable to extinguish surrounding fire. Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Flammable Limits in Air % by Volume: N/A
Special hazards arising from the substance or mixture: Carbon oxides and fumes.
Special Fire fighting Procedures: Firefighters should wear full protective equipment and NIOSH approved self-contained breathing apparatus.

6. SPILL OR LEAK PROCEDURES

Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment Cleanup procedures and Storage: Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite). Vacuum or sweep up and remove to an approved disposal container.

7. SPECIAL PRECAUTIONS

Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc).
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like acid chlorides, acid anhydrides, oxidizing agents, chloroformates, reducing agents.

8. SPECIAL PROTECTION INFORMATION

Respiratory Protection (Specify Type): None needed under normal conditions of use with adequate ventilation. NIOSH approved equipment should be worn if PELs are exceeded.
Ventilation Local Exhaust: Yes
Eye Protection: Splash proof chemical safety goggles should be worn at all times.
Other Protective Clothing or Equipment: Lab apron, eye wash, and safety shower.

9. PHYSICAL DATA

Appearance and Odor: Clear viscous liquid. Odor not defined.
Odor: Not available.
Odor threshold: Not available.
pH: Not available.
Relative density: 1.04
Melting Point: -60C
Boiling Point: 187C
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility(ies): Soluble in water.
Viscosity: Not available.

10. REACTIVITY DATA

Stability: It is stable
Conditions to Avoid: Heat, Dust generation.
Incompatibility (Materials to Avoid): Acid chlorides, Acid anhydrides, Oxidizing agents, Chloroformates, Reducing agents.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, fumes.
Hazardous Polymerization: Will not occur.

11. TOXICITY DATA

Acute toxicity:
LD50 Oral - Rat - 20,000 mg/kg
LD50 Dermal - Rabbit - 20,800 mg/kg
LD50 Intramuscular - Rat - 14 g/kg
LD50 Intravenous - Dog - 26 g/kg
Carcinogenicity: This product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC, NTP, ACGIH & OSHA.
Mutagenic Effects: Not available.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.

12. ECOLOGICAL DATA

Toxicity to fish: mortality NOEC - Pimephales promelas (fathead minnow) - 52,930 mg/l - 96 h.
Toxicity to daphnia and other aquatic invertebrates: mortality NOEC - Daphnia (water flea) - 13,020 mg/l -48 h
EC50 - Daphnia magna (Water flea) - > 10,000 mg/l - 48 h
Bioaccumulative potential: Does not bioaccumulate.
Mobility: No information available.
Results of PBT and vPvB assessment: No data available for assessment.

13. DISPOSAL INFORMATION

Waste Disposal Methods: Dispose in accordance with all applicable Federal, State and Local regulations. Follow all the pollution control rules.

14. TRANSPORT INFORMATION

DOT USA & ADR/RID: Not dangerous goods.
IMDG: Not dangerous goods.
IATA: Not dangerous goods.

15. REGULATORY INFORMATION

USA:
SARA 311/312 Hazards: Not applicable.
California Prop. 65 Components: Not listed.

16. ADDITIONAL INFORMATION

DISCLAIMER: The information and recommendations set forth herein are presented in good faith and believed correct as of the date hereof. It is compiled from various sources and it is not necessarily all inclusive nor fully adequate in every circumstance. In addition, these suggestions should not be confused with nor followed in violation of applicable laws, regulations, rules or insurance requirements applicable. This MSDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose.

Propylene Glycol USP JP BP Ph Eur IP EP FCC Food Grade Manufacturers:

Propylene Glycol Manufacturers

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11 October, 2026